NOVEL PATHOPHYSIOLOGICAL MECHANISMS OF CURRENT RESPIRATORY AND CARDIOVASCULAR DISEASES AND PROSPECTS OF DEVELOPING DIAGNOSTIC METHODS BASED ON THORACIC ELECTRICAL IMPEDANCE MEASUREMENT

Abstract

Our results let us draw the conclusion that alteration of thoracic electrical impedance is affected by geometrical forms of conductive “channels” which are airways, if we use electrical impedance spirometry, or heart chambers and main vessels in the case of high frequency electrical impedance structural and functional heart analysis. Inspiratory flow value is of great significance for the electroimpedance spirometry results, too. It has been determined that electroimpedance spirometry is a high-accuracy method for bronchial obstruction and lung parenchyma damage determination. High-frequency structural and functional electroimpedance heart analysis results correlated with structural and functional heart characteristics, which were revealed by echocardiography. The final results let us elaborate lung failure conception in the case of pneumonia. The latter results from inspiratory flow insufficiency not only in the impaired lung but also in the healthy one. The small airways disease was revealed in the group of controlled bronchial asthma patients with normal conventional sripometry results. Identical heart electrical impedance changes were revealed among arterial hypertension patients with left ventricular hypertrophy and with concentrically left ventricular remodulation signs. Opposed findings were demonstrated among the ischemic heart disease patients with dilatation of the left ventricular. These results compose the basis of structural and functional electroimpedance heart examination methodology.