Application of electrical impedance spirometry to evaluate respiratory function
DOI:
https://doi.org/10.7242/2658-705X/2019.4.1Keywords:
laboratory modeling, electrical bioimpedance, conductive fluid, aerosol, porous medium, respiratory function, spirometryAbstract
A practical method for studying the dynamics of respiratory function associated with the registration of the electrical impedance of conductive biological fluids exhaled by the patient is described. In the model measuring cell, the physical causes and patterns of change in air flow conductivity, saturated with an electrolytic fluid aerosol created by an ultrasonic nebulizer, have been investigated experimentally. The design of a new electrical impedance spirometer in the form of a mouthpiece with electrical sensors, filled with a porous medium impregnated with electrolyte, through which the patient breathes, is developed and tested. To register fluctuations in the magnitude of the impedance modulus, an original hardware and software complex is used made on the basis of a high-speed analog-to-digital converter. Based on electrical impedance analysis data, quantitative and qualitative assessment methods are proposed for the basic spirometric medical indicators characterizing the state and functioning of the patient’s breathing apparatus, such as respiration rate, entry and expiration rate, exhaled air volume, amount and concentration of exhaled lung fluid.
References
- Mislanov V.U. Issledovanie funkcii vnesnego dyhania putem izmerenia elektriceskogo impedansa legkih i dyhatel’nyh putej na razlicnyh castotah zondiruusego peremennogo toka // Vestnik sovremennoj kliniceskoj mediciny. - 2011. - T. 4. - No 4. - S. 24-28.
- Mislanov V.U., Mislanov A.V. [i dr.] Sposob diagnostiki funkcii vnesnego dyhania s pomos’u impedansnoj spirografii i programmno apparatnyj kompleks dla ego osusestvlenia // Patent RF na izobretenie No 2487662 ot 20.07.2013.
- Mislanov V.U., Zuev A.L., Ust’anceva T.L., Mislanov A.V., Savkin V.V. Issledovanie funkcii vnesnego dyhania metodom elektroimpedansnoj spirometrii: eksperimental’no - kliniceskie paralleli // Rossijskij fiziologiceskij zurnal im. I.M.Secenova. - 2013. - T. 99, - No 12. - S. 1425-1434.
- Mishlanov V., Ustyantzeva T., Nedugov V., Kalinin O., Katkova A. Bronchodilation test estimation using spirometry and electrical impedance analysis in bronchial asthma and COPD patients // Abstr. 25th Int. Congress of the European Respiratory Society, - Amsterdam, Netherlands, 26-30 September 2015. No PA2275.
- Mishlanov V., Zuev A., Koshurnikova E. The effectiveness of electrical impedance spirometry in heart insufficiency diagnostics in COPD patients // Abstr. 28th Int. Congress of the European Respiratory Society, - Paris, France, 15-19 September 2018. No PA2469.
- Zuev A.L., Sudakov A.I., Sakirov N.V. Eksperimental’noe izucenie elektriceskoj provodimosti potoka aerozola vydyhaemogo vozduha // Tez. dokl. XH Zimnej skoly po mehanike splosnyh sred, - Perm’, 13-16 fevrala 2017. - Ekaterinburg: RIO UrO RAN, 2017. C. 142.
- Zuev A.L., Mislanov A.V., Polakov V.B. Eksperimental’noe izucenie izmenenij elektriceskogo impedansa vozdusnyh kanalov, nasysennyh aerozolem rastvora elektrolita // Izvestia UgoZapadnogo gosudarstvennogo universiteta. Ser.: Upravlenie, vycislitel’naa tehnika, informatika. Medicinskoe priborostroenie. - 2018. - T. 8. - No 1 (26). - S. 41-53.
- Zuev A.L., Sudakov A.I., Sakirov N.V. Izucenie izmenenia elektriceskoj provodimosti poristoj sredy pri provedenii elektroimpedansnoj spirometrii // Tez. dokl. X^I Zimnej skoly po mehanike splosnyh sred, Perm’, 18-22 fevrala 2019. - Perm’: PFIC UrO RAN, 2019. C. 126.
- Zuev A.L., Sudakov A.I., Sakirov N.V. Sposob impedansnoj spirografii dla izucenia dinamiki dyhatel’noj funkcii celoveka i apparatno programmnyj kompleks dla ego osusestvlenia // Patent Rossijskoj Federacii na izobretenie No 2682936 ot 22.03.2019.
- Zuev A.L., Mislanov V.U., Sudakov A.I., Sakirov N.V. Avtomatizirovannyj pribornyj kompleks dla izmerenia elektriceskogo impedansa biologiceskih sred // Izvestia Ugo-Zapadnogo gosudarstvennogo universiteta. Ser.: Upravlenie, vycislitel’naa tehnika, informatika. Medicinskoe priborostroenie. - 2019.- T. 9. - No 2. - S. 6-21.