Modelling the impulse distribution, delay and block in the electrical conduction system of the heart bundles

Authors

  • I.N. Vasserman Institute of Continuous Media Mechanics UB RAS
  • A.P. Shestakov Institute of Continuous Media Mechanics UB RAS

DOI:

https://doi.org/10.7242/1998-2097/2018.3.2

Keywords:

electrical conduction system of the heart, bundle branch block, electrodynamics, finite element method

Abstract

In the article the excitatory irradiation in the electrical conduction system was numerically modeled. The overview of transmembrane potential of electrical conduction system was given. The Luo-Rudi model (2011) was chosen for the investigation. A finite element model of the electrical conduction system was built in which the latter was regarded as a one-dimensional sequence of cells connected at the edges. Based on the elaborated model one of the mechanisms of a bundle branch block was investigated. A Y-shaped structure which models the move from the common trunk of the bundle of His to the bundle branches was investigated. The results show that depending on the conductivity of certain parts of the electrical conduction system of the heart three regimes might occur: excitation advancing through branching, complete block or excitation advancing with delay. Conductivity Value Domains for the common trunk of the bundle of His and the bundle branches in which each of the regimes occurs were obtained. The role of quick and slow sodium channels when the regime with delay occurs is considered

Author Biographies

  • I.N. Vasserman, Institute of Continuous Media Mechanics UB RAS
    кандидат физико-математических наук, научный сотрудник
  • A.P. Shestakov, Institute of Continuous Media Mechanics UB RAS
    младший научный сотрудник, ИМСС УрО РАН

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Published

2018-11-02

Issue

No. 3 (2018)

Section

Research: theory and experiment

How to Cite

Vasserman, I. ., & Shestakov, A. . (2018). Modelling the impulse distribution, delay and block in the electrical conduction system of the heart bundles. Perm Federal Research Centre Journal, 3, 17-24. https://doi.org/10.7242/1998-2097/2018.3.2