SYNTHESIS OF NEW BIOLOGICALLY ACTIVE PYRIMIDINECARBOXAMIDES CLASS SUBSTANCE WITH HIGH ANALGESIC ACTIVITY

Authors

  • N.A. Buzmakova Perm Pharmaceutical Academy

DOI:

Keywords:

Biginelli reaction, pyrimidine derivatives, analgesic activity, acute toxicity

Abstract

The new pyrimidine derivatives were synthesized by the modified three-component Biginelli reaction. During the screening study of their biological activities the new substance of pyrimidine-5- carboxamides with high analgesic activity and low toxicity were selected.

Supporting Agencies
Работа выполнена при финансовой поддержке Фонда содействия развитию малых форм предприятий в научно-технической сфере.

Author Biography

  • N.A. Buzmakova, Perm Pharmaceutical Academy
    аспирант кафедры общей и органической химии, Пермская государственная фармацевтическая академия (ПГФА), 614000, г. Пермь, ул. Полевая, 2; e-mail: ledysummer@mail.ru

References

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Published

2015-10-14

Issue

No. 2 (2015)

Section

Research: theory and experiment

How to Cite

Buzmakova, N. . (2015). SYNTHESIS OF NEW BIOLOGICALLY ACTIVE PYRIMIDINECARBOXAMIDES CLASS SUBSTANCE WITH HIGH ANALGESIC ACTIVITY. Perm Federal Research Centre Journal, 2, 15-16. https://journal.permsc.ru/index.php/pscj/article/view/PSCJ2015n2p2